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Allopurinol Lawsuit

If you or someone you love has developed Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), or has experienced any other adverse event as a result of taking Allopurinol, you might be entitled to legal recourse against the drug manufacturer.

The attorneys at the Ketterer, Browne & Anderson are investigating cases on behalf of patients injured as a result of using this drug, and are available to answer your questions. Call one of our attorneys to discuss your legal rights and the appropriate next steps for your case.


What is Allopurinol?

Most commonly referred to by its generic name, Allopurinol (or Zyloprim) is a type of medication used to treat hyperuricemia, which occurs in individuals who have an excess of uric acid in blood plasma, as well as individuals suffering from chronic gout. Allopurinol belongs to a group of medications called xanthine oxidase inhibitors, which work to weaken the production of uric acid in the body.

Allopurinol has been available on the U.S. market since the mid-1960s. Allopurinol is sold under a variety of generic names by a number of different drug manufacturers, including Prometheus, which manufactures brand-name Zyloprim. Other names used for Allopurinol include:

  • Allohexal
  • Allosig
  • Milurit
  • Alloril
  • Progout
  • Zyloprim
  • Zyloric
  • Zyrik
  • Aluron

The FDA initially approved Allopurinol for treatment of hyperuricemia. Allopurinol is also used to treat ischemic reperfusion injury, protozoal infections, and kidney stones.


Side Effects of Allopurinol Use

Unfortunately, Allopurinol has several adverse side effects. If you have experienced side effects related to Allopurinol use, you should report your injuries to the FDA by way of their MedWatch Adverse Event Reporting site, or by calling 1-800-332-1088. Side effects of Allopurinol use include, but are not limited to, the following:

  • Stevens-Johnson Syndrome (SJS)
  • Toxic Epidermal Necrolysis (TEN)
  • Severe Rash
  • Hepatitis
  • Eosinophilia
  • Lesions
  • Ulcers
  • High Fever
  • Sore Throat
  • Extreme Fatigue
  • Pancytopenia
  • Poor or reduced Renal Function
  • Hypersensitivity Syndrome

In rare cases, Allopurinal use can cause cytopenias, which cause a reduction in the number of blood cells in the body. Certain adverse drug interactions may increase the risk of side effects, including amoxicillin and Thiasize diuretics.

Other side effects indicative of adverse drug interaction with Allopurinol include:

  • Upset stomach
  • Diarrhea
  • Drowsiness
  • Painful urination
  • Swelling of the lips and mouth
  • Fever
  • Flu-like symptoms
  • Chronic itching
  • Unintentional weight loss
  • Dark Urine
  • Joint pain
  • Yellowing eyes

Allopurinol use can lead to severe allergic reactions. Bad reactions to allopurinol can cause hives, rashes, scaly skin, red or purple spots, fever, chills and swelling of the face and throat. If you are having an allergic reaction while taking Allopurinol, call your health care provider immediately, as your reaction could be serious.


Allopurinol and Stevens-Johnson Syndrome (SJS)

Allopurinol use can lead to contraction of Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN). Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis are serious and potentially life-threatening skin conditions that cause severe and painful rashes all over the body and cause the epidermis to peel away from lower layers of the skin. For more information about this and other skin conditions, please visit our Stevens-Johnson Syndrome page. If you are experiencing symptoms of SJS or TEN,  seek medical attention immediately, as these conditions almost always require immediate hospitalization.


What happens if I stop taking Allopurinol?

Many patients believe that gout is a temporary disease, and that they do not need to continue the use of Allopurinol based on reports of adverse events. Gout is a chronic disease that requires continued treatment. It is important to contact your healthcare provider before you attempt to cease use of Allopurinol, as a “cold turkey” approach could be dangerous to your health. If you immediately stop treatment, the uric acid levels in your blood and urine can remain dangerously elevated, thereby exacerbating the symptoms of gout and kidney stones. Contact your doctor to discuss an appropriate step-down course of treatment.


I’ve taken Allopurinol – what should I do next?

If you or a loved one have taken Allopurinol and experienced any adverse side effects, such as Stevens-Johnson Syndrome (SJS) or toxic epidermal necrolysis (TEN), it is essential to contact a personal injury attorney at Ketterer, Browne & Anderson. Our attorneys are experienced with complex pharmaceutical litigation and can advise you of your rights and appropriate next steps. Call our team today to discuss your legal claim.