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PPI Lawsuit

Studies and research have found that PPIs or proton pump inhibitors have been associated with an increased risk of kidney damage, kidney failure, and other health damage. If you have taken or are currently taking any kind of proton pump inhibitor drugs such as Prilosec OTC or Nexium 24HR, then you may be entitled to compensation for pain and suffering, medical bills, and wage loss. Contact KBA Attorneys for a free case evaluation, and we will provide you with the help you need to reach a settlement.

While there is no way to reverse any damage these drugs have done to your body, there is still time to get the compensation you deserve so that you can continue moving forward in life. If you suspect that any type of proton pump inhibitor drug has caused you or a loved one serious harm, then call KBA Attorneys today.


What is PPI?

PPIs are drugs associated with a group of drugs that are used to treat gastroesophageal reflux disorder (GERD) and various issues related to stomach acid. These drugs have become the number one selling drugs in America, and PPI drugs are available as prescribed medication and also as an over-the-counter medication. They are an effective method of treatment for gastric acid diseases.

Proton pumps in the human body are responsible for creating hydrochloric acid in the stomach. This hydrochloric acid in the stomach is needed to digest foods. There is a muscle between the esophagus and the stomach, and in some instances, the muscle does not close properly. This results in stomach acid rising towards the throat, causing pain in the chest or esophagus areas. What the proton pump inhibitor drugs do to help this issue is to reduce the amount of hydrochloric acid produced by the proton pumps.


List of Popular PPI Drugs

  • Omeprazole (Prilosec, Prilosec OTC)
  • Aspirin and omeprazole (Yosprala)
  • Lansoprazole (Prevacid, Prevacid IV, Prevacid 24-Hour)
  • Dexlansoprazole (Dexilent, Dexilent Solutab)
  • Rabeprazole (Aciphex, Aciphex Sprinkle)
  • Pantoprazole (Protonix)
  • Esomeprazole (Nexium, Nexium IV, Nexium 24 HR)
  • Esomeprazole magnesium/naproxen (Vimovo)
  • Omeprazole/sodium bicarbonate (Zegerid, Zegerid OTC)

Who Needs PPI Drugs?

Proton pump inhibitor drugs are prescribed and bought over-the-counter by those who experience conditions that create an overproduction of stomach acid or are exacerbated by stomach acid. People who suffer common symptom such as heartburn also use proton pump inhibitor drugs. The use of PPIs can be related to the treatment of the following conditions:

1. Acid Reflux (also called gastroesophageal reflux disease (GERD))

This condition occurs when the stomach acid rises to the esophagus, backups into the esophagus or throat, and causes heartburn. Acid reflux, or GERD, is the most common reason why people use proton pump inhibitor drugs. People with GERD will typically experience chest pain, throat pain, regurgitation, and nausea. Complicated cases of GERD will cause ulcers, Barrett’s esophagus, asthma, laryngeal inflammation, lung infection, and fluid collection in the sinuses.

2. Zollinger-Ellison Syndrome

This condition is rare and is associated with issues of the digestive system and the overproduction of stomach acid. The main sign of Zollinger-Ellison Syndrome is the development of tumors called gastrinomas. These tumors form in the pancreas and upper area of the small intestine or duodenum. Symptoms of Zollinger-Ellison Syndrome include nausea, bloating, gas, weight loss, loss of appetite, and vomiting.

3. Erosive Esophagitis

The esophagus is a muscular tube that transfers food from your mouth to your stomach. This condition occurs when there is inflammation of the esophagus caused by stomach acid. Erosive esophagitis causes pain when swallowing and pain in the chest. Symptoms of erosive esophagitis include acid regurgitation, heartburn, and pain when swallowing, chest pain, food impaction, and difficulty swallowing.

4. Helicobacter Pylori Infection

This infection occurs when the bacteria called Helicobacter pylori or H. pylori infects your stomach. About 30 to 40 percent of people in America get a Helicobacter pylori infection, and it is most common during childhood. Symptoms of Helicobacter pylori infections include stomach pain, loss of appetite, nausea, gas, bloating, and weight loss.

5. Duodenal or Stomach Ulcers

The duodenum is the upper part of your small intestine and a duodenal ulcer forms in the lining of the duodenum. Helicobacter pylori is a major cause of duodenal ulcers because this bacteria can cause your duodenum lining to become inflamed and vulnerable to ulcers.


Common Side Effects of PPI Drugs

While proton pump inhibitors are effective drugs, they can also be quite harmful if not taken correctly. These adverse effects explain the dangers of taking a PPI drug and why one should think twice before buying a box. It is recommended that high doses of any PPI drug are to be avoided to avoid severe long-term side effects. Some common side effects of PPI drugs include the following:

  • Stomach Pain
  • Diarrhea
  • Headaches
  • Nausea
  • Dry mouth
  • Vomiting
  • Dizziness
  • Gas
  • Constipation
  • Drowsiness
  • Rashes
  • Nervousness

Long-Term Severe Side Effects of PPI Drugs

The drug interactions of consumers buying over-the-counter drugs are difficult to regulate. That is why it is imperative for pharmaceutical companies to make sure consumers are made aware of all potential side effects. It is also essential for these pharmaceutical companies to perform all clinical tests on the drug and ensure that they are ready for general purchase.

Unfortunately, these pharmaceutical companies are usually only concerned about money so they will do everything they can to get their product out in the market. They may even provide clinical data to the FDA that isn’t 100% accurate. As a result, their drugs are made widely available to the public, in turn, the public suffers.

Here are some long-term severe side effects that are potentially related to the use of PPIs:

1. Clostridium Difficile Infection

Clostridium Difficile is a bacteria that causes diarrhea and other harsh intestinal conditions. A safety announcement was made by the FDA in 2012, stating that the use of proton pump inhibitors may be associated with an increased risk of Clostridium Difficile.

2. Bone Fractures

Some bone fractures occur from high force or impact, while other bone fractures occur from a medical condition that weakens the bones. Another safety announcement was made by the FDA in 2011, stating that long-term use of prescription proton pump inhibitor drugs may cause low serum magnesium levels. Low magnesium levels result in weak bones, thus making people more susceptible to fractures of the hip and other bones.

3. Chronic Kidney Disease

This condition is related to the kidneys gradual loss of functionality over time. This damage to the kidneys is associated with the use of proton pump inhibitor drugs. Patients who have regularly taken PPI drugs over a long period have a higher risk of developing chronic kidney disease. According to a study published in the U.S. National Library of Medicine National Institutes of Health, patients that use proton pump inhibitor drugs such as Prilosec have about a 20 to 50 percent higher risk of chronic kidney failure.

4. Heart Attacks

A study by Houston Methodist and Stanford University found that PPI drugs increase the risk of heart attacks. Using PPI drugs could potentially interfere with the body’s blood vessels, which could result in issues of the heart. Dr. John Cooke of the Houston Methodist Research Institute found that drugs such as Nexium raise the general population’s risk of heart attacks by 15 to 20 percent. The study also found that the drug accelerates aging, which increases heart attack risks.

5. Community-Acquired Pneumonia

Pneumonia is a severe type of lung infection, and community-acquired pneumonia is when you are infected in a community setting. A study published in 2010 by The Pharmaceutical Journal found that the use of proton pump inhibitor drugs has been suggested as a risk factor for community-acquired pneumonia.


Why should you file a PPI Lawsuit?

The pharmaceutical company that manufactures drugs like Prilosec and Nexium, which are two kinds of PPIs, has faced numerous lawsuits in the past. A critical lawsuit filed against Prilosec and Nexium was filed in 2015 regarding their warning label. The plaintiff claimed that the warning label on the packages of these PPI drugs does not make it clear to consumers what all of the side effects area. AstraZeneca was sued for illegal marketing and mis-selling of their product because they created a generic version of these drugs to avoid liability and settled for $20 million.

The PPI lawsuit that can be claimed against AstraZeneca aims at their failure to adequately warn consumers and doctors about the potentially severe side effects. These side effects include an increased risk of kidney injuries, kidney failure, and kidney disease. If you have taken Prilosec, Prilosec OTC, Nexium, Nexium 24HR, or similar a drug and as a result have experienced any type of kidney damage, kidney injury, or other types of bodily harm, you may be entitled to file a claim. We highly recommend contacting our law firm, KBA Attorneys, to receive a free case evaluation and learn about the best options for your claims.

Call today at (855) 281-2571 or email us at info@kbaattorneys.com to get in touch with a Nexium Lawsuit attorney who will review your case.nd settled for $20 million.

The PPI lawsuit that can be claimed against AstraZeneca aims at their failure to adequately warn consumers and doctors about the potentially severe side effects. These side effects include an increased risk of kidney injuries, kidney failure, and kidney disease. If you have taken Prilosec, Prilosec OTC, Nexium, Nexium 24HR, or similar a drug and as a result have experienced any type of kidney damage, kidney injury, or other types of bodily harm, you may be entitled to file a claim. We highly recommend contacting our law firm, KBA Attorneys, to receive a free case evaluation and learn about the best options for your claims.

Call today at (855) 281-2571 or email us at info@kbaattorneys.com to get in touch with a Nexium Lawsuit attorney who will review your case.