According to a study included in the Journal of the American Medical Association published February 2016, researchers found that patients who were taking Nexium or other proton pump inhibitors had a 20% to 50% increased risk of chronic kidney disease. Nexium is an over-the-counter and prescribed medication that is used to treat frequent heartburn and has become one of the best selling drugs on the market.
Drugs such as Nexium and similar drugs are used to treat esophageal diseases such as gastroesophageal reflux disease and conditions such as acid reflux and stomach ulcers. There are over 15 million Americans who use proton pump inhibitors such as Nexium. While the widespread use of these drugs seems like a success, many users were not aware of the risk of kidney failure associated with Nexium and other PPIs.
Nexium, also known by its generic name esomeprazole magnesium, is considered to be a proton pump inhibitor, similar to medications such as Prilosec. These proton pumps are enzymes that create the hydrochloric acid stored in your stomach. This acid is what your body needs to digest foods, but there may be instances in some people where the muscle that is between your stomach and esophagus won’t close correctly, resulting in acid moving up to your esophagus. When acid moves up to your esophagus, you will feel a painful burning feeling in your chest and throat areas associated with gastroesophageal reflux disease (GERD).
Nexium works to decrease the amount of acid that is created by your proton pumps and treats conditions such as:
The most frequently asked question by patients are concerns over side-effects when they begin to use prescribed, or over-the-counter drugs concern the side effects. Unfortunately, many medications sold to the public do not go through extensive clinical tests before distributed to pharmacies and stores. This lack of testing means that until patients have regularly used them, many side effects of medications go undiscovered until it’s too late. Drug companies will often refuse to acknowledge any safety issue related to their products unless there is an enormous amount of scientific evidence that proves the adverse side effects.
Proton pump inhibitors (PPI) have been on the market since 1990, and since then, more and more information regarding their dangers have become known. For example, patients who have used PPIs are long periods have demonstrated low magnesium levels. Warnings were also posted that connected proton pump inhibitors to bone fractures. The FDA has had to repeatedly force these drug companies to include warnings about multiple long-term side effects of their products. We recommend that if you are taking, or are planning to use Nexium, call your doctor for medical advice regarding side effects. Learn as much as you can, and make sure that your doctor is regulating your drug use.
Common side effects of Nexium include:
While Nexium has the typical side effects of any proton pump inhibitor medication, the FDA, multiple studies, and patients have all reported more long-term severe side effects. Keep in mind that if you are experiencing any of the below conditions due to Nexium, then we recommend you to call your doctor for medical advice about side effects.
Researchers from Houston Methodist and Stanford University completed studies with results that say Nexium may raise the risk of heart attacks. Using Nexium could potentially interfere with the body’s blood vessels which could result in heart-related issues. Dr. John Cooke of Houston Methodist Research Institute found that drugs such as Nexium, raise the general population’s risk of heart attacks by 15 to 20 percent. The study also found that the drug accelerates aging which increases the risk of heart attacks.
Also known as AKI, acute kidney injury is when the kidneys suddenly shut down over a few hours or a few days in some cases. Studies have found the acute kidney injury could be related to the usage of proton pump inhibitors such as Nexium. According to a study done by CMAJ Open, older adults who are using Nexium and similar drugs have an increased risk of acute kidney injury and should take the medication in moderation if needed. Administration of this drug should be monitored carefully because acute kidney injury can cause serious harm to the body. Acute kidney injury is potentially reversible. However, if not treated quickly the condition could worsen and could lead to the severity of chronic kidney disease.
Acute interstitial nephritis is a condition related to the inflammation of the kidneys and the spaces between the kidney tubules, caused by the side effects of certain drugs such as Nexium. Acute interstitial nephritis is a major cause of renal failure. Kidney or renal failure is when the kidneys stop working correctly and are unable to work on their own to remove/filter the waste from the body’s blood. To treat kidney failure, a patient has limited options. Hemodialysis uses medical devices that move your blood through a filter outside your body, removing wastes. Another option for renal or kidney failure would be a kidney transplant. According to a study done by researchers from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System, out of 125,000 patients, more than half of them didn’t experience acute kidney failure before taking drugs like Nexium. This correlation means that these drugs have the long-term side effect of permanently damaging a patient’s kidneys or even renal failure.
By the time a diagnosis for chronic kidney disease comes to a patient, their kidneys are already in terrible shape. Patients who have regularly taken Nexium and similar medications over a long period have a higher risk of developing chronic kidney disease. This condition is related to the kidneys gradual loss of functionality and continuous damage directly related to the use of drugs such as Nexium. The longer a patient has taken proton pump inhibitor drugs, the higher the risk.
The drug manufacturer for Nexium has not made it widely known to patients and doctors that this drug has side effects that could result in kidney damage. Over recent years, Nexium has created multiple lawsuits and more lawsuits will follow. Manufactured by AstraZeneca, Nexium was approved by the FDA in 2001. The over-the-counter version of Nexium which is called Nexium 24HR was put out into the market in 2014.
When AstraZeneca introduced Nexium to consumers, they labeled the common side effects such as diarrhea, stomach pain, headaches, allergic reactions, nausea, and dizziness. As consumers continued to buy and use this drug, more severe side effects came to light. The four severe side effects listed above are just some of the impact that patients have experienced because of long-term use of Nexium and similar drugs. This lawsuit is arguing that the manufacturer of Nexium, AstraZeneca failed to appropriately warn consumers and doctors about the severe long-term side effects of Nexium. By filing a lawsuit, you are also alerting the FDA about this issue. Every time a pharmaceutical company faces a lawsuit, they must notify the FDA.
Pharmaceutical companies like AstraZeneca have made billions of dollars from Nexium and Prilosec at the expense of the general consumer’s health. Companies like AstraZeneca also understand that it is challenging to pull their products from the market. AstraZeneca will continue to disregard any allegations stating that their drugs are permanently damaging their consumers’ kidneys or they will make minimal effort to address the situation. The FDA has not taken actions against AstraZeneca, and both have refused to issue any recall on Nexium.
The two most commonly prescribed proton pump inhibitors are Nexium and Prilosec. Both of these two drugs manufactured by AstraZeneca and are available over-the-counter. Nexium and Prilosec both treat issues related to stomach acid and heartburn.
Approved by the FDA in 1989 for prescription use, Prilosec (omeprazole) was the first proton pump inhibitor introduced to the market. Then in 2003 the name changed to Prilosec OTC and was then available for over-the-counter purchase.
The Cerner Multum Drug Database offers an industry leading resource to find reliable information about the medications that you use and how to safely use them. This database aids the KBA Attorneys law firm but providing us with pertinent drug information. Visit their website by clicking here.
KBA Attorneys are offering our professional law services to those who have suffered from kidney failure and other kidney injuries caused by the commonly prescribed proton pump inhibitor, Nexium. If you have taken Nexium, Nexium 24HR, or a similar drug such as Prilosec and as a result have experienced any kidney damage, kidney injury, or other types of bodily harm; you may be entitled to compensation. We highly recommend contacting our law firm, KBA Attorneys, to receive a free case evaluation and find the best options for your claims.
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